Association between vitamin D receptor BsmI polymorphism and bone mineral density in pediatric patients
نویسندگان
چکیده
منابع مشابه
Association between vitamin D receptor BsmI polymorphism and bone mineral density in pediatric patients
BACKGROUND Vitamin D and the vitamin D receptor (VDR) are important in the metabolic processes that affect bone mineral density (BMD). However, the effect of VDR BsmI polymorphism on BMD in pediatric patients is still unclear. METHODS Eligible studies were identified from the following electronic databases: PubMed, Embase, the Cochrane Library, and the Chinese CNKI and Wanfang databases befor...
متن کاملAssociation between Vitamin D Receptor Gene BsmI Polymorphism and Bone Mineral Density in A Population of 146 Iranian Women
OBJECTIVE Osteoporosis is a bone disorder that reduces bone mineral density (BMD) and leads to bone fracture. In addition to different factors, gene polymorphisms have been revealed to be associated with osteoporosis. In this study, we investigated the association between the BsmI polymorphism of vitamin D receptor (VDR) gene (rs1544410) and BMD in a population of Iranian women. MATERIALS AND...
متن کاملassociation between vitamin d receptor gene bsmi polymorphism and bone mineral density in a population of 146 iranian women
objective: osteoporosis is a bone disorder that reduces bone mineral density (bmd) and leads to bone fracture. in addition to different factors, gene polymorphisms have been revealed to be associated with osteoporosis. in this study, we investigated the association between the bsmi polymorphism of vitamin d receptor (vdr) gene (rs1544410) and bmd in a population of iranian women. materials and ...
متن کاملThe Association of Vitamin D Receptor Gene BsmI Polymorphism with Multiple Sclerosis in Iranian Patients
Background & Aims: 1,25-dihydroxyvitamin D3 (1,25 (OH)2 D3), the biologically active form of vitamin D, exerts an immunosuppressive effect through binding to its specific nuclear receptor. The present case-control study was done to examine the possible association of BsmI polymorphism in vitamin D receptor gene (VDR gene) with severity of multiple sclerosis (MS). Methods: 267 Iranian patients w...
متن کاملLack of association of vitamin D receptor BsmI gene polymorphism with bone mineral density in Spanish postmenopausal women
Osteoporosis is a polygenic disorder that is determined by the effects of several genes, each with relatively modest effects on bone mass. The aim of this study was to determine whether the vitamin D receptor single nucleotide polymorphism BsmI is associated with bone mineral density (BMD) in Spanish postmenopausal women. A total of 210 unrelated healthy postmenopausal women aged 60 ± 8 years w...
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ژورنال
عنوان ژورنال: Medicine
سال: 2017
ISSN: 0025-7974
DOI: 10.1097/md.0000000000006718